Research Topics
Our lab consists of a number of multi and cross disciplinary projects working on the development of physical and computational sciences as applied to medical imaging. Our research ranges from development of diffuse optical techniques, to computational tools assisting image guided interventions.
Optical Instrumentation
Despite counting with several commercial diffuse optical devices in our lab, we actively develop purpose-driven optical technology to tackle research problems. Our lab focuses on developing systems such as devices for diffuse optical tomography (DOT), fluorescence imaging, and most recently, diffuse correlation spectroscopy (DCS).
Light Transport in Biological Tissue
We actively work on analytical and numerical models for studying light propagation in turbid media such as biological tissue. Part of our work is available for free use, such as the FEM-based NIRFAST.
Functional Neuroimaging Analysis
Great part of our work encompasses better and more general ways to rationalize data provided by functional near-infrared spectroscopy (fNIRS). To this end, we study the biases present in the fNIRS signal and proposing potential ways to circumvent them or alleviate their impact, improving the signal quality. We also make use of physical models to develop associative and causal statistical models for analyzing the brain connectivity. More recently, part of our group exploits topological spaces such as manifolds to encode observations about brain behaviour and from there answer segregational and integration questions about brain function.
Current Research Projects
- Mild Traumatic Brain Injury Biomarker Study, a prospective cohort biomarker study of military and civilian participants with mTBI: mTBI-Predict
- BioSMART: BIOreactor Spatial Mapping and Actuation in Real Time
- Live monitoring of foreign-body response in animals by diffuse Raman spectroscopy
- Next generation deep tissue quantitative optical imaging